Resident Research and Scholarly Activity


The University of Missouri Health Care OB/GYN residency program provides comprehensive support for participation in resident research and scholarly activity. Opportunities to participate in clinical, surgical, and educational research abound. In 2007-2008, four residents published peer-reviewed publications and five presented their work at national meetings. If you are interested in pursuing a fellowship or simply more interested in mechanisms of disease, our six research faculty members share over 2,000 square feet of wet lab space that is available to support select bench research projects.

Jennifer Luth, PhD teaches chief resident Erin Tuller, MD how to extract RNA from endometrial cancers to evaluate haptoglobin expression.
Postdoc Jennifer Luth, PhD teaches chief resident Erin Tuller, MD how to extract RNA from endometrial cancers to evaluate haptoglobin expression. Dr. Tuller began a fellowship in gynecologic oncology at the University of Oklahoma in 2007.


Research faculty members and their general areas of interest:

  • Kathy L. Sharpe-Timms, PhD, HCLD: Endometriosis, endometrial cancer, metalloproteinases, haptoglobin.

  • Susan C. Nagel, PhD: Environmental estrogens, birth defects, endometriosis.

  • Gary F. Clark, PhD: Maternal-fetal immune tolerance; glycobiology; HIV, immune privilege of human cancers, sperm-egg binding.

  • Danny J. Schust, MD: Recurrent pregnancy loss, in vitro fertilization, placentation, maternal-fetal immune tolerance.

  • Breton F. Barrier, MD: Maternal-fetal immune tolerance, ovarian cancer pathogenesis, HLA-G, primate models, surgical educational research, minimally invasive surgery research (NOTES).

  • Ray Foster, MD: Urinary incontinence, pelvic organ prolapse, primate models.

Below is a list of publications in peer-reviewed journals since 2006, authored by residents and faculty in our department. Manuscripts with resident authorship are marked by asterisk (*). (Current as of February 2008.)

2008

*Christian J, Barrier BF, Miedema B, Thaler K. Culdoscopy: Foundation for natural orifice surgery, past present and future. J Am Coll Surg [accepted for publication January 2008]

*Barrier BF, Frazier SR, Brennaman LM, Taylor JC, Ramshaw BJ. Catamenial appendicitis. Obstet Gynecol 2008; 111:558-61.

Luth JA, Hubbard GB, Dick EJ Jr, Frazier SR, Barrier BF. Characterization of spontaneous mammary gland carcinomas in female baboons. J Med Primatol 2008; 37:55-61.

2007

Winn HN. Group B streptococcus infection in pregnancy. Clin Perinatol 2007;34:387-92. Review.

*Barrier BF, Allison J, Hubbard GB, Dick EJ Jr, Brasky KM, Schust DJ. Spontaneous adenomyosis in the chimpanzee (Pan troglodytes): a first report and review of the primate literature: case report. Hum Reprod 2007; 22:1714-7. Review.

Foster RT Sr, Borawski KM, South MM, Weidner AC, Webster GD, Amundsen CL. A randomized, controlled trial evaluating 2 techniques of postoperative bladder testing after transvaginal surgery. Am J Obstet Gynecol 2007; 197:627.

Foster RT Sr, Barber MD, Parasio MF, Walters MD, Weidner AC, Amundsen CL. A prospective assessment of overactive bladder symptoms in a cohort of elderly women who underwent transvaginal surgery for advanced pelvic organ prolapse. Am J Obstet Gynecol 2007; 197:82.

Foster RT Sr. Mal de Mayo. Emerg Infect Dis 2007; 13:337-40.

Foster RT Sr. Academic medical centers, private industry, and clinical trials: how do we achieve fairness, objectivity, and balance? Int Urogynecol J Pelvic Floor Dysfunct 2007; 18:233-5.

Foster RT Sr, Anoia EJ, Webster GD, Amundsen CL. In patients undergoing neuromodulation for intractable urge incontinence a reduction in 24-hr pad weight after the initial test stimulation best predicts long-term patient satisfaction. Neurourol Urodyn 2007; 26:213-7.

Foster RT, Amundsen CL, Webster GD. The utility of magnetic resonance imaging for diagnosis and surgical planning before transvaginal periurethral diverticulectomy in women. Int Urogynecol J Pelvic Floor Dysfunct 2007; 18:315-9.

Borawski KM, Foster RT, Webster GD, Amundsen CL. Predicting implantation with a neuromodulator using two different test stimulation techniques: A prospective randomized study in urge incontinent women. Neurourol Urodyn 2007; 26:14-8.

South MM, Foster RT, Webster GD, Weidner AC, Amundsen CL. Surgical excision of eroded mesh after prior abdominal sacrocolpopexy. Am J Obstet Gynecol 2007; 197:615.

Pang PC, Tissot B, Drobnis EZ, Sutovsky P, Morris HR, Clark GF, Dell A. Expression of bisecting type and Lewisx/Lewisy terminated N-glycans on human sperm. J Biol Chem 2007; 282:36593-602.

Anderson BJ, Haimovici F, Ginsburg ES, Schust DJ, Wayne PM. In vitro fertilization and acupuncture: clinical efficacy and mechanistic basis. Altern Ther Health Med 2007; 13:38-48. Review.

Kawana K, Quayle AJ, Ficarra M, Ibana JA, Shen L, Kawana Y, Yang H, Marrero L, Yavagal S, Greene SJ, Zhang YX, Pyles RB, Blumberg RS, Schust DJ. CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity. J Biol Chem 2007; 282:7368-75.

Sutton-Smith M, Wong NK, Khoo KH, Wu SW, Yu SY, Patankar MS, Easton R, Lattanzio FA, Morris HR, Dell A, Clark GF. Analysis of protein-linked glycosylation in a sperm-somatic cell adhesion system. Glycobiology 2007; 17:553-67.

Barrier BF, Dick EJ Jr, Butler SD, Hubbard GB.Endometriosis involving the ileocecal junction with regional lymph node involvement in the baboon: a first report and striking pathological finding identical between the human and the baboon. Hum Reprod 2007; 22:272-4.

Barrier BF, Joiner LL, Jimenez JB, Leland MM. External cephalic version of the term breech baboon (Papio sp.) fetus. J Med Primatol 2007; 36:148-50.

2006

Barrier BF, Kendall BS, Sharpe-Timms K, Kost ER. Characterization of human leukocyte antigen-G (HLA-G) expression in endometrial adenocarcinoma. Gynecol Oncol 2006; 103:25-30.

Pierce LM, Rankin MR, Foster RT, Dolber PC, Coates KW, Kuehl TJ, Thor KB. Distribution and immunohistochemical characterization of primary afferent neurons innervating the levator ani muscle of the female squirrel monkey. Am J Obstet Gynecol 2006; 195:987-96.

*Barrier BF, Kendall BS, Ryan CE, Sharpe-Timms KL. HLA-G is expressed by the glandular epithelium of peritoneal endometriosis but not in eutopic endometrium. Hum Reprod 2006; 21:864-9.

Cameo P, Szmidt M, Strakova Z, Mavrogianis P, Sharpe-Timms KL, Fazleabas AT. Decidualization regulates the expression of the endometrial chorionic gonadotropin receptor in the primate. Biol Reprod 2006; 75:681-9.

Clark GF, Dell A. Molecular models for murine sperm-egg binding. J Biol Chem 2006; 281:13853-6. Review.

Welshons WV, Nagel SC, vom Saal FS. Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology 2006; 147(6 Suppl):S56-69. Review.

Chalabi S, Panico M, Sutton-Smith M, Haslam SM, Patankar MS, Lattanzio FA, Morris HR, Clark GF, Dell A. Differential O-glycosylation of a conserved domain expressed in murine and human ZP3. Biochemistry 2006; 45:637-47.

Textbooks and Book Chapters

Timms KS, Barrier BF, Nagel SC. Chapter 37. Endometrial paradigms. In: The Endometrium, Ed: Asgi Fazleabas, 2008.

Cardiovascular Disease in Women. Winn, H.N. and Dellsperger, K.C. (Eds.). Taylor and Francis Books, Ltd. London, UK. 2006.

Clinical Maternal-Fetal Medicine. Winn, H.N. and Hobbins, J.C. (Eds.), Parthenon, London. 2001.




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