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Missouri Orthopaedic Institute

Mizzou BioJoint Center

The Mizzou BioJoint Center provides cutting-edge treatments for joint problems to restore patients’ joint function and quality of life. Our physicians and scientists work together daily to find better solutions for the most common orthopaedic problems.

To learn more, please contact the BioJoint team at 573-884-3077 or

The BioJoint Team works with you from the start to develop a comprehensive care strategy that will meet your needs and goals. The team works with you every step of the way, from identifying non-operative procedures (such as physical therapy) that could help alleviate symptoms, to performing innovative surgeries using technology and techniques that have been developed and enhanced at the Missouri Orthopaedic Institute.

The center’s team is focused on delivering the ultimate in patient care and customer service. From the minute you make your first appointment to the time of your last follow-up, our team will be available to you. Helping you find hotel rooms, providing suggestions for local dining for you and your family and answering questions you may have — we will do everything possible to provide you the great care and attention you deserve.

Why a BioJoint surgery?

BioJoint surgery involves a biologic or “natural” surgical procedure to treat your joint problem. Our surgeons use natural tissue grafts of tendons, ligaments, cartilage, menisci and/or bone to restore your joint’s function. BioJoint surgery can be a great option for patients wishing to delay or eliminate the need for a total joint replacement. Your BioJoint doctor will work with you to develop the best BioJoint strategy for your specific needs and goals, whether that is a BioJoint surgery, non-operative management, or traditional total joint replacement.

Where do BioJoint grafts come from?

The Mizzou BioJoint Center uses accredited tissue banks throughout the country to help match the right graft with each patient. These grafts come from organ donors. This gracious gift is then tested and prepared for transplant; one donor is often able to improve the lives of multiple patients.

The tissue banks we use include the Musculosketal Transplant Foundation, RTI International and JRF Ortho.

Are donor grafts safe?

Yes. Each graft is tested extensively for disease or defect before being placed in a patient. With orthopaedic tissue, rejection is not a problem and patients do not need anti-rejection medications. Instead of the extensive testing and matching needed to use grafts for other parts of the body, such as a kidney for kidney transplant, orthopaedic grafts rely solely on the size of the patient compared to the donor for graft matching.

Can BioJoint help me?

BioJoint may be right for you if you experience any of these symptoms:

  • Consistent pain in joint
  • Catching and clicking in joint
  • Joint swelling and pain that won’t go away
  • Feeling of a “loose joint”
  • Inability to perform your job or daily activities because of joint problems

Mizzou BioJoint care team

  • James Cook, PhD, DVM, Director of Operations and Scientific Director
  • James Stannard, MD, Medical Director
  • Brett Crist, MD, Orthopaedic Surgeon
  • Matt Smith, MD, Orthopaedic Surgeon
  • Bob Schaal, PT, Physical Therapist
  • Nichole Wilson, RN, Nurse Clinician
  • Allison Shaw, RN, Surgery Coordinator
  • Carey Ruekberg, Clinical Coordinator
  • Kylee Rucinski, Outcomes Coordinator

What can I expect?

The typical process for a Mizzou BioJoint patient includes an initial appointment, pre-operation imaging, waiting for a graft match, surgery and follow-up appointments. For details, please download this informational handout.


Contact Us

For more information, please contact our team at:

Mizzou BioJoint Center
Missouri Orthopaedic Institute
1100 Virginia Ave.
Columbia, MO 65212


Cook's Recipe

Dr. Jimi Cook

MIZZOU magazine highlights how MU dynamo Jimi Cook is helping revolutionize knee replacement surgery.

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Making a Splash

Loren Figueroa

Loren Figueroa’s knee injury nearly ended her athletic career as a diver on the University of Missouri’s Swim and Dive team. Following a BioJoint procedure, she returned to diving and broke Mizzou’s record in the 3-meter dive.

Loren's story

Game Changer

James Cook and James Stannard

MU researchers developed a technique to improve biologic joint replacements. Learn more about the science behind the surgery.

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In the News

Phil Bergman of KOMU-8 (Columbia, Missouri) reports in April 2015 how a preservation method developed at MU doubles the life for donor tissues. BioJoint patient Dustin Nagy shares her story.