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How Roux-en-Y Gastric Bypass Works When the small functioning upper stomach pouch is full (at first this will occur with only a nibble or two), patients experience a sense of fullness. In this way, and because the appetite will also be reduced, the intake of food is dramatically limited. This is what enables weight loss. What food is eaten is handled by the body quite well. On average, patients will lose about 100 lbs. or up to two thirds of their excess weight in one year. Some people lose a little more, some a little less. Weight loss will continue during the second year at a less rapid rate. About 15 percent of patients will not lose as much weight as they would like. It is important to remember that surgery is a tool to help well motivated patients attain their desired weight loss. Patients cannot rely on the operation to do it all for them.
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