Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)

This patient population will be recruited from the cohort presenting to Women and Children's Hospital for percutaneous fixation of pediatric supracondylar humerus fractures. Participants will be asked to assent to take part in the study and their parents or guardian will be asked to sign an informed consent. Patients will be randomized to a treatment group that receives one dose of pre-operative antibiotics or one that does not.

Start Date: August 18, 2017

Completion Date: December 31, 2020

Status: Recruiting

A Multicenter Study to Evaluate Functional Outcome After Knee Replacement

To compare functional and patient reported outcome data for a consecutively enrolled group of subjects who have undergone surgery with either a ConforMIS iTotal® CR TKA or an Off-the- Shelf (OTS) system.The person conducting the functional testing will be blinded to the device implanted. Sites will perform the off-the-shelf total knees conventional instrumentation.

Start Date: July 1, 2015

Completion Date: August 31, 2025

Status: Recruiting

Clinical Assessment of the Missouri Osteochondral Allograft Preservation System - MOPS

Patients that are enrolled in this study will receive an osteochondral allograft from tissue that has been stored in the MOPS instead of the currently standard preservation system (culture media at 4 degrees Celsius). This will be the only difference in the surgical procedure between enrolled patients and non-study patients. Enrolled patients will undergo their grafting procedure as they normally would if they were not enrolled in this study. They will also receive the same care as non-study patients.

Start Date: June 30, 2015

Completion Date: June 30, 2020

Status: Recruiting

Riluzole in Spinal Cord Injury Study

At present there are over 1 million people living with Spinal Cord Injury (SCI) in North America alone, with annual costs for the acute treatment and chronic care of these patients totaling four billion dollars USD. The worldwide prevalence of SCI is unknown, with estimates ranging up to 250 million individuals. The incidence of SCI in developed countries has been estimated to be between 10 - 40 cases per million inhabitants.

Start Date: August 31, 2013

Completion Date: December 31, 2024

Status: Recruiting