Nicholas LeFevre, MD, grew up in Columbia, Missouri, and attended medical school at the University of Missouri. After graduation, he completed a four-year Family Medicine residency with an integrated fellowship in high-risk obstetrics at the Lawrence Family Medicine Residency near Boston, Massachusetts. He spent four years working as core faculty at the John Peter Smith Family Medicine residency and the TCU and UNTHSC School of Medicine in Fort Worth, Texas, before joining the University of Missouri faculty in 2021. He enjoys taking care of families over time including office-based primary care for children and adults, obstetrics, and hospital medicine. He actively publishes and teaches on topics related to evidence-based medicine, obstetrics, addiction and point-of-care ultrasound. He has a special area of interest and expertise in addiction medicine and is fluent in Spanish. Outside of work, he enjoys spending time with his wife and young son.

Education & Training

Medical School

University of Missouri School of Medicine


Family Medicine

  • Greater Lawrence Family Practice Residency Program


High-Risk Obstetrics

  • Greater Lawrence Family Practice Residency Program


American Board of Family Medicine


MU Health Care participates with most major managed care organizations. To find out whether MU Health Care is a participating provider in your insurance plan or network, or for information on co-payments and deductibles, please contact your insurance carrier directly.

Academic Information

Assistant Professor

Areas of Expertise

  • Obstetric and women's health care
  • Evidence-based adult and pediatric care
  • Addiction Medicine
  • Point-of-care ultrasound


  • LeFevre N., Krumm E.
    Labor Dystocia in Nulliparous Women.
    American Family Physician. 2021; 103(2): 9096.
  • LeFevre N., Mischel N.
    Beta Blockers for Suspected or Diagnosed Myocardial Infarction.
    American Family Physician. 2020; 102(11); 666-667.
  • LeFevre N., Youngs K, Lutchman K, Story E.
    Does Adding ezetimibe to statin therapy improve cardiovascular outcomes in patients with diabetes?
    Evidence-Based Practice: August 2020; 23(8):33-34.
  • LeFevre N., Sundermeyer, R.
    Fetal Aneuploidy: Screening and Diagnostic Testing.
    American Family Physician. 2020; 101(8):481-488.
  • LeFevre N., Krumm E.
    Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy.
    American Family Physician. 2019; 100(7):403-405.
  • LeFevre, N.
    Cochrane for Clinicians: Aromatase Inhibitors such as letrozole (femara) vs. clomiphene (clomid) for subfertile women with PCOS.
    American Family Physician. 2019 May 1; 99(9):545-546.
  • LeFevre N., Leveroni M. Doust J.,
    Heart failure (diastolic).
    Essential Evidence Plus. October 2018. John Wiley & Sons, Inc. Available online at: https://www.essentialevidenceplus.com/content/eee/32.
  • Smith A, Barr WB, Bassett-Novoa E, LeFevre N.
    Maternity Care Update: Postpartum Care.
    FP essentials. 2018; 467:33-36.
  • Smith A, Barr WB, Bassett-Novoa E, LeFevre N.
    Maternity Care Update: Labor and Delivery.
    FP essentials. 2018; 467:25-32.
  • Smith A, Barr WB, Bassett-Novoa E, LeFevre N.
    Maternity Care Update: Prenatal Care and Specific Conditions.
    FP essentials. 2018; 467:17-24.
  • Smith A, Barr WB, Bassett-Novoa E, LeFevre N.
    Maternity Care Update: Preconception Care.
    FP essentials. 2018; 467:11-16.