Locations

University Hospital
1 Hospital Dr
Columbia, MO

Phone: 573-884-3278

Other Phone Numbers:

Phone: (573) 882-4141

Get Directions

1. University Hospital

1 Hospital Dr
Columbia, MO
Phone: 573-884-3278
Other Phone Numbers:
Phone: (573) 882-4141
View Details
Get Directions

Profile

Gender

Male

Education & Training

Medical School

University of Illinois at Chicago College of Medicine

Internship

Internal Medicine

  • University of Michigan Medical School

Residency

Internal Medicine

  • University of Michigan Medical School

Fellowship

Cardiovascular Disease

  • Mayo Clinic

Hematology

  • Mayo Clinic

Boards

American Board of Internal Medicine
American Board of IM - Cardiovascular Disease

Insurances

MU Health Care participates with most major managed care organizations. To find out whether MU Health Care is a participating provider in your insurance plan or network, or for information on co-payments and deductibles, please contact your insurance carrier directly.

Academic Information

Professor
Senior Associate Dean for Research

Office

1 Hospital Drive
Columbia, MO 65212
United States

P. 573-882-2296
F. 573-884-7743

Research Interests

  • Vascular biology
  • Thrombosis
  • Atherosclerosis

Awards & Honors

  • 1978 B.S., Magna cum Laude, University of Illinois
  • 1980 Phi Beta Kappa
  • 1981 Alpha Omega Alpha
  • 1982 President, Alpha Omega Alpha, University of Illinois Chapter
  • 1982 M.D. with Honors, University of Illinois
  • 1982 Finalist, William J. Grove Award (Outstanding Graduate), University of Illinois
  • 1989 Finalist, Young Investigators' Award Competition, American College of Cardiology
  • 1990 Outstanding Achievement Award for a Subspecialty Trainee in Cardiovascular Disease (Research), Mayo Clinic
  • 1992 Winner, Young Investigator Prizes in Thrombosis, American Heart Association
  • 1994 Academic Exchange Award, American College of Cardiology/European Society of Cardiology
  • 1998 Finalist, Update in Thrombolysis 1998 Research Award Competition
  • 2004- J.W. and Lois Winifred Stafford Distinguished Chair in Diabetes and Cardiovascular Research, University of Missouri
  • 2006 Thrombosis Special Recognition Award, ATVB Council of American Heart Association
  • 2011 Visiting Professor, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN
  • 2016 Chair, NIH Special Emphasis Panel ZRG1 VH-J, October 27 2016

Grants

  • NIH R01
    “Roles of Plasminogen Activator Inhibitor-1 and Vitronectin in Failure of Coronary Revascularization”
  • NIH/NHLBI Program Project Grant
    “Molecular Genetics of Coagulation Disorders” PI: D. Ginsburg
    Dr. Fay is Co-Investigator (10% effort) on Project 3: (“Thrombosis and Hemostasis in Host Defense from Bacterial Infection”, PI: H. Sun)
  • NIH R44
    “Improved long-term biocompatibility of coronary stents by plasma coating process” PI: M. Chen (APT Therapeutics). Missouri Life Sciences Trust Fund. “Targeting Plasminogen Activator Inhibitor-1 to Inhibit Restenosis”

Publications

  • Ji* Y, Weng* Z, Fish P, Goyal N, Luo M, Myears SP, Strawn TL, Chandrasekar B, Wu J, Fay WP (*these authors contributed equally to this article). Pharmacological Targeting of Plasminogen Activator Inhibitor-1 Decreases Vascular Smooth Muscle Cell Migration and Neointima Formation. Arterioscler Thromb Vasc Biol. 2016;36:2167-2175. PMCID: PMC5102271.
  • Khoobchandani M, Katti K, Maxwell A, Fay WP*, Katti KV* (*co-senior author). Laminin Receptor-Avid Nanotherapeutic EGCg-AuNPs as a potential alternative therapeutic approach to prevent restenosis. Int J Mol Sci. 2016 Mar 1;17. doi: 10.3390/ijms17030316.
  • Somanna NK, Valente AJ, Krenz M, Fay WP, Delafontaine P, Chandrasekar B. The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4. J Cell Physiol. 2016;231:1130-41. doi: 10.1002/jcp.25210.
  • Chen N, Ren M, Li R, Deng X, Li Y, Yan K, Xiao L, Yang Y, Wang L, Luo M, Fay WP, Wu J: Bevacizumab promotes venous thromboembolism through the induction of PAI-1 in a mouse xenograft model of human lung carcinoma. Molecular Cancer 2015; 14:140. PMCID: PMC4517418.
  • Wu J, Strawn TL, Luo M, Wang L, Li R, Ren M, Xia J, Zhang Z, Ma W, Luo T, Lawrence DA, Fay WP: Plasminogen Activator Inhibitor-1 Inhibits Angiogenic Signaling by Uncoupling VEGF Receptor-2-αVβ3 Integrin Cross-talk. Arterioscler Thromb Vasc Biol. 2015; 35:111-120. PMCID: PMC4270947.
  • Ji Y, Fish PM, Strawn TL, Lohman AW, Wu J, Szalai AJ, Fay WP: C-reactive protein induces expression of tissue factor and plasminogen activator inhibitor-1 and promotes fibrin accumulation in vein grafts. J Thromb Haemost. 2014;12:1667-77. PMCID: PMC4194135.
  • Sidhu MS, Aggarwal K, Fay WP: Acute Isolated Right Ventricular Myocardial Infarction Masquerading as Acute Anterior Myocardial Infarction. BMJ Case Reports. 2014; doi:10.1136/bcr-2012-008087.
  • Zuidema MY, Peyton K, Fay WP, Durante W, Korthuis, RJ: Antecedent hydrogen sulfide elicits an anti-inflammatory phenotype in postischemic murine small intestine: Role of heme oxygenase-1. Am J Physiol Heart Circ Physiol 2011;301:H888-H894. PMCID: 21666111.