Now Enrolling Allergy Clinical Trials

ENT clinical trials stock image

Pediatric House Dust Mite Studies (MT-11 & MT-12)

Does your child wake up most mornings congested? Does your child have worse allergies in the winter, especially when you turn on the heat for the first time? Does your child have known house dust mite allergies? If you answered yes to any of these questions and you are not receiving allergy drops or shots, your child might be a candidate for one of our two clinical trials.

Our first clinical trial is for children ages 5-17 who have house dust mite allergies and moderate to severe asthma that is not well controlled. Participants in this study will have 11 site visits over two years.

Our second clinical trial is for children age 5-11 with house dust mite allergies who may or may not also have asthma. For this study, asthma patients must have mild or moderate asthma that is well controlled. Participants for this study will have seven site visits over approximately one year.

Participants in both studies will undergo screenings before final selection for the study. To learn more, contact the ENT research office at entresearch@missouri.edu or 573-882-2549.

New study for Chronic Spontaneous/Idiopathic Urticaria (PEARL-1)

We are excited to announce a new clinical trial using biologics for the treatment of chronic spontaneous urticaria — also known as hives. To be eligible, patients must be:

  • 12 years of age or older.
  • Diagnosed with chronic spontaneous urticaria more than six months ago.
  • Using antihistamines but not getting better.
  • Not currently using a biologic.
  • Not pregnant, nursing or planning to become pregnant.

This is a 16-month study with visits to the site once per month. Potential participants will go through two screenings before final selection for the study. To learn more, contact the ENT research office at entresearch@missouri.edu or 573-882-2549.

Non-surgical Clinical Trial for Patients with Chronic Sinusitis

Are you an adult (18 years or older) diagnosed with chronic sinusitis? Have you been having nasal congestion, runny nose, drainage down the back of your throat, facial pain or pressure and a reduction or loss of smell? If you said yes to both of these questions, then you might be a candidate for our clinical trial. This clinical trial uses a new nasal spray that puts the medicine deeper in your sinuses, where it is needed the most. This is a seven-month trial requiring six or seven visits to the site. To learn more, contact the ENT research office at entresearch@missouri.edu or 573-882-2549.

Contact the ENT Research Center to Learn More

Read more stories like this